This Mississippi Pot Roast is the kind of comfort food that never goes out of style. It’s rich, hearty, and soul-satisfying — the perfect blend of savory, tangy, and buttery flavors. Whether you cook it all day in the slow cooker or fast-track it with the Instant Pot, one thing’s for sure: it’ll be a family favorite for years to come. Once you try it this way, you’ll never go back to plain pot roast again.
Prep Time10 minutesmins
Cook Time3 hourshrs
Slow Cooker Method (On Low)8 hourshrs
Total Time10 minutesmins
Course: Beef Recipes, Comfort Food, Dinner Recipes, Favorites, Main Course
Salt, pepper, garlic powder, and onion powder, to taste
Avocado oil or neutral oilfor searing
Instructions
Step 1 – Prep & Sear the Roast
Allow your 3–4 lb chuck roast to rest at room temperature for about 20 minutes.
Season generously with salt, pepper, garlic powder, and onion powder.
Heat a drizzle of avocado oil in a Dutch oven or large skillet over high heat.
Sear the roast for 2–4 minutes per side until a deep brown crust forms.
This locks in flavor and helps create a beautiful gravy later.
Remove the roast and set aside.
Pro Tip: You can add extra veggies like carrots or potatoes if you want a heartier roast, but traditionally, this dish keeps it simple with just onions, garlic, and pepperoncini.
Step 2 – Choose Your Cooking Method
Oven Method (Classic & Tender)
Return the seared roast to the Dutch oven.
Sprinkle in ranch seasoning and au jus mix.
Add 4–8 pepperoncini peppers and 2 tablespoon of their brine for tang.
Toss in 1 sprig of rosemary and pour in ½ quart beef stock.
Add ½ stick to 1 stick of butter on top.
Cover and bake at 350°F for 3–4 hours, until fork-tender.
Shred the roast and stir to combine everything into a rich, buttery gravy.
Strain the juice from the pot, whisk 1 tablespoon flour + 2 tablespoon water, and stir in near the end for a thicker gravy.
Step 2: Choose Your Cooking Method
Slow Cooker Method (Set It & Forget It)
Place the seared roast in your slow cooker.
Add ranch mix, au jus mix, butter, onions, garlic, peppers, and beef stock.
Cover and cook on LOW for 8 hours or HIGH for 4–5 hours, until tender.
Strain the juice from the pot, whisk 1 tablespoon flour + 2 tablespoon water, and stir in near the end for a thicker gravy.
Shred and mix into the juices before serving.
Pressure Cooker / Instant Pot Method (Fast & Flavorful)
On the Sauté setting, sear the roast on all sides.
Add butter, flour, garlic, onions, ranch mix, au jus, stock, and peppers.
Seal and cook on High Pressure for 60 minutes.
Let pressure release naturally for 15 minutes, then quick release any remaining steam.
Shred the roast and mix into the flavorful gravy — ready in under 90 minutes total!
Notes
Serving Suggestions
Serve over mashed potatoes, buttered noodles, or white rice.
Pair with roasted vegetables, green beans, or cornbread for a complete Southern meal.
Garnish with a few extra pepperoncini slices and a drizzle of that buttery gravy.